Ozempic can be combined with healthy eating and regular exercise. Ozempic, the fourth once-weekly glucagon-like peptide-1 receptor antagonist (GLP-1RA) medication, is now available on the market. It follows Trulicity (dulaglutide), Bydureon(exenatide extended delivery), and Tanzeum [albiglutide]. Ozempic will be available in the U.S. before Tanzeum is discontinued due to problems with sales. Ozempic is different from other GLP-1 RAs that are once a week. It has shown the fastest and most effective results in reducing blood sugar and body weight. A pill version of Ozempic has also been developed and is currently being evaluated in clinical trials.
What is the Ozempic Method of Working?
Ozempic, like the other GLP-1 RA products, is once-weekly. It is synthetic but acts in the same way as the GLP-1 hormone that the body naturally produces. It stimulates insulin production by the pancreas (only when glucose levels are high), reduces liver glucose production, and makes people feel fuller quicker. People lose weight because their glucose levels are more controlled over the course of the day, as well as after meals.
What is Ozempic used for?
Ozempic is available in prefilled disposable injector pen sizes of 0.5mg and 1 mg. Ozempic is only required to be administered once per week due to its long half-life of seven days. Make one day in the week your Ozempic Day (e.g. Sunday). You can also mark your calendar and set an alarm on your phone to remind you.
You can remember your day if you are unable to remember it within five days. If that happens, give it immediately and designate the day as your NEW Ozempic Day. You should wait two days before you administer your next dose if it is less than 2 days.
Pick an administration site that is at least 2 inches from your stomach, thigh or upper arm. Place the pen tip on your skin after you have uncapped the pen. Now you can press the button to inject. To ensure that the dose is delivered completely, keep the button down for between 5-10 seconds. Rotate within the same side each week to use a different injection site. Each pen contains only four doses. The pen should be thrown away once it is empty. Keep new pens in a refrigerator away from light and in the original box.
What can you expect?
Ozempic increases fasting and postprandial blood glucose levels. However, due to its long-acting formula, it has a stronger effect than fasting plasma glucose. Your A1c will decrease by approximately 1.2 to 1.8% depending on how much you take. Like other GLP-1 RAs Ozempic is associated with low risks of hypoglycemia (low blood glucose). Ozempic has a 13-pound weight loss, which is significantly more than the reports of other GLP-1 RRAs.
Ozempic also reduces the risk of heart attack and stroke, according to clinical data. These benefits will be confirmed by long-term studies.
Ozempic can cause stomach emptying slowing down, just like other GLP-1 RAs. You may also experience mild to moderate stomach upset or nausea. These symptoms typically disappear within a few days of starting Ozempic. Reduce the amount of food you eat throughout the day to reduce indigestion symptoms.
Are you a Ozempic user?
Your medical and family history will be discussed with your provider before you start Ozempic. Discuss with your provider if you have any problems with your kidneys or pancreas, if you are pregnant or plan to become pregnant, and if there is a family history of thyroid cancer or severe gastrointestinal disease (GI) disease. It is also recommended to have an annual dilated vision exam. To avoid interactions, inform your provider about all prescriptions, herbal medicines, and over-the-counter medications.
The bottom line:
Ozempic has a high A1c reduction, which is comparable to other GLP-1-RAs. It also offers moderate weight loss and possibly cardiovascular protection. Future studies will give clinicians more insight into which GLP-1 RA is most effective for each patient. Discuss with your doctor if Ozempic may be the best option to help you reach your glucose goals.